Friday, September 5


09:00 – 09:10

Opening

Jesús F. San-Miguel
Heinz Ludwig

09:10 – 10:25

PLENARY SESSION 1: MYELOMA BIOLOGY

ModeratorFelipe Prósper
09:10 - 09:30How is the transition from MGUS into MM?
Bruno Paiva
09:30 - 09:50What should I know about systemic manifestations in MGUS patients?
Joan Bladé
09:50 - 10:10Can we identify and treat high risk Smoldering Myeloma patients?
Dr. Karthik Ramasamy
10:10 - 10:25Experts' discussion around 5 burning questions:

  1. 1. What is the meaning of genetic and epigenetic changes in MGUS and SMM?

  2. 2. When to atribute clinical manifestations to the M-component?

  3. 3. Optimal treatment in MGUS with renal impairment

  4. 4. How to define High Risk SMM?

  5. 5. To treat or no to treat SMM
Discussants: Dr. Prósper, Dr. Paiva, Dr. Bladé, Dr. Ramasamy, Dr. Ludwig, Dr. San-Miguel

10:25 – 10:35

Break

10:35 – 11:50

PLENARY SESSION 2: NEW TOOLS FOR PROGNOSTICATION AND MONITORING IN MM

ModeratorHeinz Ludwig
10:35 - 10:55Genomics in myeloma?: new tools and new definitions.
Herve Avet-Loiseau
10:55 - 11:15Why MRD should be implemented in trials and routine practice? to whom, when and with which technique?
Noemí Puig
11:15 - 11:35Should I use CT, MRI or CT-PET?
Elena Zamagni
11:35 - 11:50Experts' discussion around 5 burning questions:

  1. 1. Optimal techniques for genetics

  2. 2. Optimal MRD technique

  3. 3. Prognostic factors or biomarker for treatment

  4. 4. Should we stratify patients?

  5. 5. Should we implement PET in routine clinical practice?
Discussants: Dr. Ludwig, Dr. Avet-Loiseau, Dr. Puig, Dr. Zamagni, Dr. Manier, Dr. Paiva, Dr. Terpos

11:50 – 12:00

Break

12:00 – 13:15

PLENARY SESSION 3: CHALLENGING TOPICS

ModeratorJesús F. San-Miguel
12:00 - 12:201. Emergencies and supportive care (cord compression, RI, bone disease)
Evangelos Terpos
12:20 - 12:402. What are the clues for difficult to treat MM (extramedullary, CNS, solitary)?
Kwee Yong
12:40 - 13:003. How to deal with immunotherpy adverse events
Cyrille Touzeau
13:00 - 13:15Questions & discussion

13:15 – 14:00

Lunch

14:00 – 14:30

PLENARY SESSION 4: KEYNOTE LECTURE

ModeratorJesús F. San-Miguel
14:00 - 14:20How to prevent and treat infections in myeloma
Heinz Ludwig
14:20 - 14:30Questions & discussion

14:30 – 14:40

Break

14:40 – 15:55

PLENARY SESSION 5: FRONT LINE TREATMENT FOR YOUNG PATIENTS WITH MM

ModeratorJesús F. San-Miguel
14:40 - 15:00Is there an optimal induction? Transplant for all?
Elias Mai
15:00 - 15:20What type of consolidation and maintenance is recommended?
Pieter Sonneveld
15:20 - 15:40How to approach high-risk patients?
Martin Kaiser
15:40 - 15:55Experts' discussion around 5 burning questions:

  1. 1. Best induction

  2. 2. Early vs. late transplant

  3. 3. One vs. two

  4. 4. Consolidation & maintenance

  5. 5. High risk
Discussants: Dr. San-Miguel, Dr. Mai, Dr. Sonneveld, Dr. Kaiser, Dr. Bladé, Dr. Touzeau

15:55 – 16:05

Break

16:05 – 17:00

PLENARY SESSION 6: FRONT LINE TREATMENT FOR ELDERLY PATIENTS WITH MM

Moderator Heinz Ludwig
16:05 - 16:25How should I treat elderly patients?
Salomon Manier
16:25 - 16:45How should I treat elderly frail patients?
Alessandra Larocca
16:45 - 17:00Experts' discussion around 5 burning questions:

  1. 1. Optimal combination and duration

  2. 2. Maintenance/continuous

  3. 3. Do we need alkylators?

  4. 4. High risk

  5. 5. Frailty
Discussants: Dr. Ludwig, Dr. Manier, Dr. Larocca, Dr. Delforge, Dr. Ramasamy