10:30 – 10:45
Welcome
| Dr. Mariano Provencio, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
10:45 – 13:50
SESSION I – MOLECULAR ANALYSIS IN GECP STUDIES: REVENTION, ADJUVANT AND PERIOPERATIVE
| Chairs | Dr. José Luis González Larriba, Hospital Clínico San Carlos, Madrid Dr. Mariano Provencio, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 10:45 - 10:55 | Residential radon and molecular alterations in non-small cell lung cancer Dr. Virginia Calvo, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 10:55 - 11:15 | NADIM adjuvant trial Dr. Bartomeu Massuti, Hospital General Univ. Dr. Balmis, Alicante |
| 11:15 - 11:30 | Biomarker analysis of the NADIM adjuvant trial Dr. Alberto Cruz, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 11:30 - 11:45 | Tissue Matters: The envolving role of pathology in immunotherapy Dr. Ignacio Wistuba, Moffit Cancer Center, Florida, USA |
| 11:45 - 11:55 | Predictive biomarkers for perioperative chemoimmunotherapy Dr. Alberto Cruz, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 11:55 - 12:05 | TCR repertoire as an emerging biomarker Dr. Cristina Martínez-Toledo, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 12:05 - 12:20 | Role of neutrophil extracellular traps in tumor response to immunotherapy Dr. Muhammad Shazad, McGill University, Montreal, Canada |
| 12:20 - 12:50 | Discussion |
| 12:50 - 13:10 | Profiling cell identity and tissue architecture with single-cell and spatial transcriptomics Dr. Linghua Wang, University of Texas, MD Anderson Cancer Center in Houston, Texas, USA |
| 13:10 - 13:20 | Mapping resistance: uncovering altered tumor pathways through spatial transcriptomics Dr. Marta Molina, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 13:20 - 13:30 | Single-cell resolution of peripheral immune remodeling by neoadjuvant chemoimmunotherapy in lung cancer Dr. Juan Manuel Gutiérrez, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 13:30 - 13:50 | Discussion |
13:50 – 14:50
Lunch
14:50 – 15:40
SESSION II – TUMOR MICROENVIROMENT
| Chairs | Dr. Enric Carcereny, ICO-Hospital Germans Trias i Pujol, Badalona, Barcelona Dr. Manuel Dómine, Hospital Univ. Fundación Jiménez Díaz, Madrid |
| 14:50 - 15:05 | BCR repertoire dynamics in tumor and blood reveal signatures of response to neoadjuvant chemoimmunotherapy Dr. Belén Sierra, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 15:05 - 15:15 | Neoadjuvant chemoimmunotherapy triggers TLS induction with distinct functional states in pathologic complete responders Dr. Ángeles Gil-Gonzalez, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 15:15 - 15:25 | Perioperative chemoimmunotherapy induces strong immune responses and long-term survival in patients with HLA class I-deficient non-small cell lung cancer Dr. Marta Molina, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 15:25 - 15:40 | Discussion |
15:40 – 16:55
SESSION III – MICROBIOME
| Chairs | Dr. Paula Espinosa, Hospital General Univ. de Valencia Dr. Rosario García Campelo, Hospital Univ. de la Coruña |
| 15:40 - 16:00 | Beyond the tumor: The microbiome as a key player in immune modulation Dr. Lisa Derosa, Institut Gustave Roussy, Paris, France |
| 16:00 - 16:10 | The Migrant trial Dr. Rosa del Campo, Hospital Univ. Ramón y Cajal, Madrid |
| 16:10 - 16:20 | Microbiome analysis in NADIM II trial Dr. Alejandro Rodríguez, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 16:20 - 16:30 | Metabolomic profiling reveals predictive biomarkers of response to perioperative chemoimmunotherapy in NSCLC Dr. Atocha Romero, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 16:30 - 16:40 | CUBIK trial biomarker study Dr. Lucía Robado de Lope, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |
| 16:40 - 16:55 | Discussion |
16:55 – 17:25
Coffee break
17:25 – 18:20
SESSION IV – ONGOING STUDY PROPOSALS WITH POSSIBLE COLLABORATION WITH GECP
| Chairs | Dr. Florentino Hernando Trancho, Hospital Clínico San Carlos, Madrid Dr. Bartomeu Massuti, Hospital General Univ. Dr. Balmis, Alicante |
| 17:25 - 17:35 | Immuno Lung Dr. María Saigi, ICO Badalona, Barcelona |
| 17:35 - 17:45 | Epigenetic signature Dr. Alejandro Olivares, Hospital Clínico Univ. de Salamanca |
| 17:45 - 17:55 | Investigation of the microbiota in relation to the response to immunotherapy in patients affected by advanced non-small cell lung cancer Dr. Juan Vicente Valor, Hospital Clínico San Carlos, Madrid |
| 17:55 - 18:05 | Exploring galectin-1 as a new therapeutic target in small cell lung cancer (SCLC) Dr. Arancha Cebrián, Hospital Univ. Fundación Jiménez Díaz, Madrid |
| 18:05 - 18:20 | Discussion |
18:20 -18:40
SESSION V – PROFFERED POSTER
| Poster review presenter: Dr. Manuel Cobo, Hospital Regional Univ. de Málaga |
18:40
Closing remarks
| Dr. Mariano Provencio, Hospital Univ. Puerta De Hierro, Majadahonda, Madrid |